Genome BioInformatics Research Lab

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Computational Analysis of Splicing

A database (SpliceDB) of known mammalian splice site sequences has been developed. Weight matrices were built for the major splice groups, which can be incorporated into gene prediction programs. SpliceDB is available at the computational genomic Web server of the Sanger Center and has a mirror site at SoftBerry.

Relevant publications

  • M. Burset, I.A. Seledtsov and V.V. Solovyev.
    "SpliceDB: Database of canonical and non-canonical mammalian splice sites."
    Nucleic Acid Research 29(1):255-259 (2001) [Abstract]

  • M. Burset, I.A. Seledtsov and V.V. Solovyev.
    "Analysis of canonical and non-canonical splice sites in mammalian genomes."
    Nucleic Acid Research 28(21):4364-4375 (2000) [Abstract]

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